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Product Information

Rispoval 4 is an off-white freeze-dried pellet containing attenuated strains of BRSV (Bovine Respiratory Syncytial Virus) and PI3 (Parainfluenza type 3) viruses supplied together with a suspension containing inactivated, adjuvanted IBR (Infectious Bovine Rhinotracheitis – BHV-1) and BVD (Bovine Viral Diarrhoea) cytopathic and non-cytopathic Type 1 viruses. For active immunisation of cattle to reduce infection, clinical signs and respiratory disease caused by BRSV, IBR and PI3; and leucopenia and viraemia caused by the BVD Type 1 cytopathic and non-cytopathic strains. Do not vaccinate pregnant animals. Very occasionally, administration of the vaccine may be followed by a mild transient reaction at the injection site up to 0.5cm and completely resolved within 15 days. No information is available on the safety and efficacy from the concurrent use of this vaccine with any other product except Rispoval Pasteurella. Therefore the safety and efficacy of this product when used with any other (either when used on the same day or at different times) has not been demonstrated. Do not mix with any other vaccine/immunological product. Withdrawal period: Zero days. Store away from light between + 2° and + 8°C. Do not freeze. Reconstituted vaccine should be used within 2 hours. Dispose of waste material by boiling, incineration or immersion in an approved disinfectant in accordance with national requirements. Keep out of the sight and reach of children. For animal treatment only.

Rispoval 3 is a freeze dried fraction containing modified live PI3 (Parainfluenza 3) virus, strain RLB103 and modified live BRSV (Bovine Respiratory Syncytial virus) strain 375 supplied with a liquid fraction containing inactivated BVDV (Bovine Viral Diarrhoea Virus) type 1, strains 5960 (cytopathic) and 6309 (non-cytopathic). For the active immunisation of calves from 12 weeks of age to reduce virus excretion and the clinical signs caused by PI3 virus, reduce virus excretion caused by BRSV infection and reduce virus excretion and the severity of leucopenia induced by BVDV type 1 infection. Do not use in unhealthy animals. Do not use during pregnancy and lactation. The administration of the vaccine can lead to a transient and mild hyperthermia which can last for 2 days and to a transient, minor local inflammation reaction of up to 0.5cm which disappears within 15 days. In very rare cases, the vaccine may cause hypersensitivity reactions. In case of anaphylactic reaction, symptomatic treatment should be provided. No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be decided on a case by case basis. Do not mix with any other veterinary medicinal product. In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the doctor. Withdrawal period: Zero days. Store and transport refrigerated (+2°C to +8°C). Do not freeze. Protect from heat and light. Once reconstituted, use within 2 hours. Dispose of waste material by boiling, incineration or immersion in an appropriate disinfectant in accordance with national requirements. Keep out of the sight and reach of children. For animal treatment only.

Rispoval RS+PI3 Intranasal is a powder containing modified live Bovine parainfluenza type 3 virus (PI3V), thermosensitive strain RLB103 and modified live Bovine Respiratory Syncytial virus (BRSV), strain 375 supplied with sterile diluent for reconstitution. For active immunisation of maternally derived antibody positive or negative calves from 9 days of age against BRSV and PI3V, to reduce the mean titre and duration of excretion of both viruses. Do not use during pregnancy/lactation. Vaccinate only healthy animals. Published evidence shows that on rare occasions repeated exposure to BRSV may trigger hypersensitivity reactions. No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis. Do not mix with any other veterinary medicinal product. Withdrawal period: Zero days. Store and transport refrigerated (2°C - 8°C). Do not freeze. Protect from light. Once reconstituted use within 2 hours. Dispose of waste material by boiling, incineration or immersion in an appropriate disinfectant approved for use by the competent authorities. Keep out of the sight and reach of children. For animal treatment only.

Rispoval IBR-Marker Live is a live, freeze-dried, Infectious Bovine Rhinotracheitis (IBR)-Marker (gE-negative) vaccine. One dose (2 ml) contains: Bovine Herpes Virus type 1 (BoHV-1), strain Difivac (gE-negative) modified live (attenuated) virus For the active immunisation of cattle against IBR to reduce virus shedding and clinical signs including, in female cattle, abortions associated with BoHV-1 infection. A reduction in abortions associated with BoHV-1 infection has been demonstrated during the second trimester of gestation following challenge 28 days after vaccination. Do not use in unhealthy animals. When injected intramuscularly in very rare cases minor, transient swelling up to 3 cm in diameter, which generally subsides within 7 days, may occur at the injection site. Following intranasal inoculation slight, transient, serous nasal discharge may occur in very rare cases for up to 7 days. In very rare cases, allergic reactions may occur as with other vaccines, therefore vaccinates should be observed for approximately 30 minutes following immunisation. In those cases, anti-allergics should be administered. In some cases, the vaccine virus may be excreted after intranasal administration from vaccinated animals. Exceptional transmission of the virus from intranasally-vaccinated animals to non-vaccinated in-contact animals may occur due to the nature of the vaccine even though no verified data available would indicate that spreading of the vaccine virus occurs in a group of animals. It is recommended to vaccinate all the cattle in the herd. The presence of maternal antibodies can influence the efficacy of the vaccination. Therefore it is recommended to ascertain the immune status of calves before vaccination is started. Immunosuppressive substances e.g. corticosteroids or Bovine Viral Diarrhoea modified live vaccines, should be avoided for a period of 7 days prior to and after vaccination as this may impair the development of the immunity. Interferon sensitive products should not be applied intranasally following 5 days after intranasal vaccination. No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be decided on a case by case basis. Do not mix with any other veterinary medicinal product except diluent supplied for use with the product. In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician. Withdrawal period: Zero days. Store in a refrigerator (+2°C to +8°C). Protect from heat and light. Do not freeze. When product is withdrawn aseptically from broached vials, which are thereafter kept at +2°C to +8°C, the reconstituted vaccine can be used for one working day (8 hours). Dispose of waste material by boiling, incineration or immersion in an appropriate disinfectant approved for use by the competent authorities. Keep out of the sight and reach of children. For animal treatment only.

Tracherine is a powder containing live attenuated virus of Infectious Bovine Rhinotracheitis (IBR), strain ts RLB106 supplied with sterile diluent for reconstitution. For active immunisation of calves to reduce viral shedding and clinical signs caused by IBR. For information about side effects, precautions, warnings and contra-indications for this product, please refer to the product packaging and package leaflet. Withdrawal period: Zero days. Store and transport refrigerated (2°C - 8°C) away from light. Do not freeze. Once reconstituted use immediately. Dispose of waste material by boiling, incineration or immersion in an appropriate disinfectant approved for use by the competent authorities. Keep out of the sight and reach of children. For animal treatment only.

Imuresp RP is a powder containing live attenuated virus of Infectious Bovine Rhinotracheitis (IBR), strain ts RLB106 and live attenuated viruse of Parainfluenza type 3 (PI3), strain ts RLB 103 supplied with sterile diluent for reconstitution. For active immunisation of calves and growing cattle to reduce viral shedding and clinical signs associated with IBR and for active immunisation to reduce PI3 viral shedding from infected animals. For information about side effects, precautions, warnings and contra-indications for this product, please refer to the product packaging and package leaflet. Withdrawal period: Zero days. Store and transport refrigerated (2°C - 8°C) away from light. Do not freeze. Once reconstituted use immediately. Dispose of waste material by boiling, incineration or immersion in an appropriate disinfectant approved for use by the competent authorities. Keep out of the sight and reach of children. For animal treatment only.

For further information please refer to the product SPC or contact your veterinary surgeon or Zoetis UK ltd. 

Walton Oaks, Tadworth, Surrey, KT20 7NS

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